Caspian Journal of Internal Medicine
Babol University of Medical Sciences
Fri, Jun 27, 2025
[Archive]
Volume 16, Issue 3 (Summer 2025)
Caspian J Intern Med 2025, 16(3): 519-524 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Saraei koushki M, parizad R, Abdollahzadeh A, Separham A. Impact of HbA1c levels on coronary SYNTAX score in non-diabetic patients with ST-elevation myocardial infarction undergoing primary angioplasty: A cross-sectional study. Caspian J Intern Med 2025; 16 (3) :519-524
URL: http://caspjim.com/article-1-4249-en.html
URL: http://caspjim.com/article-1-4249-en.html
Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran , separham@gmail.com
Abstract: (96 Views)
Background: Glycated hemoglobin A1c (HbA1c) level is related to increased cardiovascular diseases (CVDs) and death, even in non-diabetic subjects. Although in ST-elevation myocardial infarction (STEMI) cases, the association between HbA1c and coronary artery disease (CAD) remains unclear.
Methods: This cross-sectional study was conducted on 167 non-diabetic STEMI patients undergoing primary percutaneous coronary intervention (PCI). The SYNTAX score was utilized to evaluate CAD severity. Cases were categorized into three groups based on the HbA1c levels: <5%, 5.1-5.9%, and 6-6.5%.
Results: SYNTAX scores significantly increased in the cases with 6 to 6.5 HbA1c levels compared to the other group (28.9±9.5 vs 21.2±5.2 vs 13.7±4.5, P=0.000). Additionally, death was more elevated in this group (4% vs 0% vs 0%, P=0.006).
Conclusion: Higher HbA1c levels are strongly associated with coronary atherosclerosis in non-diabetic patients that present with non-diabetic STEMI. Consequently, in non-diabetic STEMI patients, HbA1c may be able to predict the severity of CAD.
Methods: This cross-sectional study was conducted on 167 non-diabetic STEMI patients undergoing primary percutaneous coronary intervention (PCI). The SYNTAX score was utilized to evaluate CAD severity. Cases were categorized into three groups based on the HbA1c levels: <5%, 5.1-5.9%, and 6-6.5%.
Results: SYNTAX scores significantly increased in the cases with 6 to 6.5 HbA1c levels compared to the other group (28.9±9.5 vs 21.2±5.2 vs 13.7±4.5, P=0.000). Additionally, death was more elevated in this group (4% vs 0% vs 0%, P=0.006).
Conclusion: Higher HbA1c levels are strongly associated with coronary atherosclerosis in non-diabetic patients that present with non-diabetic STEMI. Consequently, in non-diabetic STEMI patients, HbA1c may be able to predict the severity of CAD.
Type of Study: Original Article |
Subject:
Cardiology
Received: 2024/01/16 | Accepted: 2024/06/2 | Published: 2025/06/20
Received: 2024/01/16 | Accepted: 2024/06/2 | Published: 2025/06/20
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
