en Infectious Diseases Infectious Diseases Original Article Original Article Background: Several regimens of therapy were recommended for the treatment of genital wart with different efficacies. The purpose of this study was to compare the efficacy of podophylin 20% versus trichloroacetic acid 30% in the treatment of genital wart.<br>Methods: This randomized clinical study was conducted on 120 cases with genital wart. They randomly received podophylin 20% or trichloroacetic acid 30%. All cases were followed up for 6 months. The efficacy of both regimens of therapy was compared. <br>Results: Among the 60 cases who were treated by podophylin, 56 cases (93.3%) were completely treated. From the 60 cases treated by thricholoracetic, 56 (93.3%) cases were completely treated (p>0.05). <br>Conclusion: The results show that the efficacy of both regimens of therapy are equal. Condyloma accuminata, Podophylin, Trichloroacetic acid, Treatment 16 19 http://caspjim.com/browse.php?a_code=A-10-62-5&slc_lang=en&sid=1 Sudabeh Tirgar Tabari 1003194753284600254 1003194753284600254 Yes Maryam Javadian 1003194753284600255 1003194753284600255 No Shahnaz Barat 1003194753284600256 1003194753284600256 No