en Infectious Diseases Infectious Diseases Case Series Case Series <p><font face="Times New Roman" size="3"> </font><font face="Times New Roman"><b><i><span style="color: blue font-size: 10pt"><font face="times new roman,times,serif">Background:</font> </span></i></b></font><font face="times new roman,times,serif"><span style="font-size: 10pt">Rhinocerebral mucormycosis is a fatal infection typically affecting diabetic or immunosuppressed patients. In most cases, infection is caused by inhalation of fungal spores. Mortality rate of patients is very high (40-85%)</span><font size="2"><span dir="rtl" lang="AR-SA">.</span></font></font></p> <p><font face="times new roman,times,serif"><font size="3"> </font><b><i><span style="color: blue font-size: 10pt"><font face="times new roman,times,serif">Case Presentation:</font></span></i></b><span style="font-size: 10pt"> In this study, three diabetic patients with rhinocerebral mucormycosis were presented. The etiologic agents of mucormycosis in two patients were isolated and identified by sequence analysis and data were registered in Gene bank database.</span></font></p> <p><font face="times new roman,times,serif"><font size="3"> </font><b><i><span style="color: blue font-size: 10pt"><font face="times new roman,times,serif">Conclusion</font></span></i></b><b><i><span style="color: blue font-size: 10pt"><font face="times new roman,times,serif">:</font> </span></i></b><span style="background: white font-size: 10pt">In patients with mucormeosis, early detection, surgical excision and appropriate debridement, suitable antifungal therapy, and control of risk factors like</span><span style="font-size: 10pt"> </span><font size="2"><span style="background: white">diabetes mellitus are the main parameters of successful management of this lethal infection.</span></font></font></p> <p><font face="Times New Roman" size="3"> </font></p> Rhinocerebral mucormycosis, Diabetes Mellitus, Iran 243 246 http://caspjim.com/browse.php?a_code=A-10-329-1&slc_lang=en&sid=1 Rasoul Mohammadi dr.rasoul_mohammadi@yahoo.com 10031947532846004236 10031947532846004236 No Department of Medical Parasitology and Mycology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran Mohsen Meidani meidani@med.mui.ac.ir 10031947532846004237 10031947532846004237 Yes Department of Infectious Diseases, Al-Zahra hospital, Isfahan University of Medical Sciences, Isfahan, Iran Kamyar Mostafavizadeh mostafavizadeh@med.mui.ac.ir 10031947532846004238 10031947532846004238 No Department of Infectious Diseases, Al-Zahra hospital, Isfahan University of Medical Sciences, Isfahan, Iran Bijan Iraj bijan@gmail.com 10031947532846004239 10031947532846004239 No Department of Endocrinology, Isfahan University of Medical Sciences, Isfahan, Iran Pooria Hamedani pooria.hamedani@yahoo.com 10031947532846004240 10031947532846004240 No Department of Endocrinology, Isfahan University of Medical Sciences, Isfahan, Iran Mohammad Amin Sayedain Dr.sayedain62@yahoo.com 10031947532846004241 10031947532846004241 No Department of Cardiology, Chamran Hospital (Heart Centre), Isfahan University of Medical Sciences, Isfahan, Iran Mojgan Mokhtari mokhtari@med.mui.ac.ir 10031947532846004242 10031947532846004242 No Department of Pathology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran