Caspian Journal of Internal Medicine

en Carotid endarterectomy on the course of the acute period of ischemic stroke and chronic cerebral ischemia Neurology Neurology Original Article Original Article Background: Carotid endarterectomy (CE) is currently the main surgical treatment and preventative measure for ischemic stroke (IS) in patients with atherosclerotic stenosis and carotid artery occlusion; however, there are no clear opinions regarding the effect of CE on the course of the acute period of IS and chronic cerebral ischemia (CCI). Methods: The study included 186 patients aged 45–81 years. The study population comprised two observation groups: group I included 131 patients with internal carotid artery (ICA) stenosis of more than 60% with unstable atherosclerotic plaque who underwent CE, and group II included 55 patients with ICA stenosis 60% with stable atherosclerotic plaque who did not undergo surgical treatment. The SPSS 21 package was used for statistical analysis. Results: The results of the NIHSS, Rankin, and Rivermead scales after 12 months indicated a significant positive dynamic of the neurological status in patients in the first group (2.33 ± 0.30 in the first group and 0.89 ± 0.12 in the comparison group, p < 0.05). In the acute period of IS, CE performed according to indications led to a decrease in neurological symptoms (80.9% of patients scored 0–3 points on the NIHSS scale), a decrease in the degree of disability, and an increase in mobility in patients. Conclusion: In patients who underwent the operation, disability was significantly lower 1 year after IS. сarotid endarterectomy, ischemic stroke, atherosclerotic stenosis, disability degree. 659 666 http://caspjim.com/browse.php?a_code=A-10-3491-1&slc_lang=en&sid=1 Aiym Sakhipova simvol90@mail.ru 100319475328460054836 100319475328460054836 Yes State Budgetary Healthcare Institution of the Samara region «Samara City Clinical Hospital No. 1 named after N.I. Pirogov», Astana, Kazakhstan