en Nutrition Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:13.8pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> Numerous studies have demonstrated that improving anthropometric indices through a healthy diet and exercise can aid individuals with high blood pressure. Additionally, research suggests that consuming Spirulina, a type of microalga, could positively impact body composition and anthropometric indices. The purpose of this study was to determine the effects of spirulina-fortified salad dressing on anthropometric indices and body composition in patients with hypertension. </span><br> <span style="line-height:13.8pt"><b><i><span style="color:blue">Methods</span></i></b><i><span style="color:blue">:</span></i> 48 (19 men and 22 women) patients with hypertension randomly received either spirulina-fortified salad dressing containing 2 gr spirulina (SSD, n = 22) or a placebo salad dressing (PSD, n = 19) daily for eight weeks<span style="color:black">.</span> <span style="color:black">This study was registered at </span><a href="https://www.irct.ir/" style="color:#0033cc; text-decoration:underline"><span style="color:black"><span style="text-decoration:none">https://www.irct.ir/</span></span></a><span style="color:black"> (the Iranian registry of clinical trials identifier: IRCT20200404046940N1).</span></span><br> <span style="line-height:13.8pt"><b><i><span style="color:blue">Results</span></i></b><i><span style="color:blue">:</span></i> There was a change in body composition and anthropometric indices from baseline to 8 weeks. We observed that the mean change&plusmn;SD of waist circumference after the SSD intervention (-2.86&plusmn;4.02 cm) was significantly different from that of the PSD intervention (0.38&plusmn;9.47 cm). Although no between-group difference was observed, a statistically significant reduction in body fat-free mass (FFM) occurred in the PSD group after the intervention. Meanwhile, within-group mean change&plusmn;SD of body fat-free mass (FFM, 1.04&plusmn;5.39 kg) and body fat mass (FM, -0.73&plusmn;1.83 kg) was significant only in the SSD group.&nbsp; However, no significance between-group difference was observed in terms of FFM and FM changes.</span><br> <span style="line-height:13.8pt"><b><i><span style="color:blue">Conclusion</span></i></b><i><span style="color:blue">:</span></i> The present study&rsquo;s findings suggest that consuming spirulina-fortified dressing can improve the status of risk factors associated with hypertension and cardiovascular diseases.</span></span></span><br> &nbsp; Spirulina, Anthropometric Indices, Body Composition, Hypertension, Cohen’s d Value 553 561 http://caspjim.com/browse.php?a_code=A-10-3183-1&slc_lang=en&sid=1 Elnaz Ghaem Far elnaz.ghaemfar@gmail.com 100319475328460053397 100319475328460053397 Yes Department of Food Technology, Engineering and Nutrition, Lund University, Sweden Siavash Babajafari jafaris@sums.ac.ir 100319475328460053398 100319475328460053398 No Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran Zohreh Ghaem Far zohreh.ghaemfar@gmail.com 100319475328460053399 100319475328460053399 No Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran Salman Mohammadi s.mohammadi.diet@gmail.com 100319475328460053400 100319475328460053400 No Department of Nutrition, School of Health and Nutrition, Lorestan University of Medical Sciences, Khorramabad, Iran Mehran Nouri mehran_nouri71@yahoo.com 100319475328460053401 100319475328460053401 No Infertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Javad Kojuri kojurij@yahoo.com 100319475328460053402 100319475328460053402 No Department of Cardiology, Shiraz University of Medical Sciences, Shiraz, Iran Elham Ashrafi-Dehkordi elhamashrafi@gmail.com 100319475328460053403 100319475328460053403 No Nutrition Research Center and Department of Food Hygiene and Quality Control, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran Mohammad Hossein Rahmani Mhrahmani228@gmail.com 100319475328460053404 100319475328460053404 No Clinical Education Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Seyed Mohammad Mazloomi smmazloomi@gmail.com 100319475328460053405 100319475328460053405 No Nutrition Research Center and Department of Food Hygiene and Quality Control, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran