en Cardiology Cardiology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> The coronary angiography results in a group of patients with myocardial infarction (MI) are normal or near-normal; which is<b> </b>diagnosed as myocardial infarction with non-obstructive coronary arteries (MINOCA). This study aimed to compare the mortality rate and risk factors between MINOCA and myocardial infarction with obstructive coronary artery (MI-CAD).</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Methods:</span></i></b> This retrospective cohort study was conducted from January 1, 2018, to December 31, 2019. A total of 679 patients admitted to Afshar Hospital in Yazd with a diagnosis of ST-elevation myocardial infarction (STEMI) from 2018-2019 who underwent primary Percutaneous Coronary Intervention (PCI) were enrolled in the study. Demographic, and clinical variables, ECG finding and one-year mortality, were extracted using MI registry data from the Yazd Cardiac Research Center.<span style="font-size:10.0pt"></span></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Results:</span></i></b> The estimated frequency of MINOCA was 4.6%. Patients with MINOCA (</span><br> <span style="line-height:14pt">47.14&plusmn;6.2) were younger than patients with MI-CAD (57.61&plusmn;9.1) (P <0.0001). MINOCA patients (47.4&plusmn;9.47) had a considerably greater left ventricular ejection fraction (LVEF) than MI-CAD patients (43.5&plusmn;6.8) (P =0.018). The majority site of MI in MINOCA patients was located in the non-anterior wall (p <0.0001). A comparison of MINOCA and MI-CAD patients&#39; one-year mortality&nbsp;revealed no significant difference (P =0.07). &nbsp;<b><span lang="FA" dir="RTL" style="font-size:10.0pt"></span></b></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Conclusion</span></i></b><i><span style="color:blue">:</span></i> The prevalence of patients with MINOCA in Yazd was similar to other communities. Although these patients probably do not have a better prognosis, despite being younger and having better LV systolic function and lower CAD risk factors.<span style="font-size:10.0pt"></span></span></span></span><br> &nbsp; MINOCA, MI-CAD, STEMI 109 114 http://caspjim.com/browse.php?a_code=A-10-2997-1&slc_lang=en&sid=1 Abbas Andishmand drandishmand@yahoo.com 100319475328460046522 100319475328460046522 No Department of Cardiology, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Mahmood Emami Meybodi emami.mahmood@yahoo.com 100319475328460046523 100319475328460046523 No Department of Cardiology, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Seyedeh Mahdieh Namayandeh Drnamayandeh@ssu.ac.ir 100319475328460046524 100319475328460046524 No Department of Epidemiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Hamid Reza Mohammadi h.r_mohammadi@yahoo.com 100319475328460046525 100319475328460046525 No Student Research Committee, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Mojtaba Andishmand max3d2018@hotmail.com 100319475328460046526 100319475328460046526 No Student Research Committee, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Mohammadali Zarbakhsh mohammad_zarbakhsh@yahoo.com 100319475328460046527 100319475328460046527 Yes Department of Cardiology, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Marzieh Azimizade m.azimi1400@gmail.com 100319475328460046528 100319475328460046528 No Student Research Committee, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran