en Ophtalmology Ophtalmology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> The purpose of this study was to determine the distribution of intraocular pressure (IOP) and assess its association with age, sex, systemic blood pressure, diabetes mellitus, body mass index (BMI) and tobacco smoking in Iranian elderly population.<span style="font-size:9.0pt"></span></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Methods:</span></i></b> This cohort-based, cross-sectional study assessed elderly individuals aged 60-90 years in Amirkola, northern Iran, in 2016-2017. Past medical history, blood pressure, diabetes mellitus, BMI and tobacco smoking were recorded through an interview and physical examination. IOP was assessed using non-contact tonometry.</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Results:</span></i></b> Total of 1377 individuals participated in this study, out of which 1346 IOP measurements were included for the final analysis. The mean age of participants was 69.4 &plusmn; 7.1 years and mean IOP was determined to be 16.7 &plusmn; 3.2 mmHg. Majority of the participants were males (56.1% vs 43.1%), 73.8% of participants were overweight or obese, 6.1% smoked tobacco, 28.9% had diabetes mellitus and 84.9% had higher than normal blood pressure. Through multiple regression analysis, it was determined that age (&beta;=-0.132, p<0.001) was negatively associated with IOP, and the presence of diabetes mellitus (&beta;=0.118, p<0.001), systolic blood pressure (&beta;=0.101, p<0.001), and BMI (&beta;=0.020, P=0.020) were positively associated with IOP.<b><i><span style="color:blue"></span></i></b></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Conclusion</span></i></b><i><span style="color:blue">:</span></i> Mean IOP of individuals in this study was higher than average based on other studies. Age, was negatively and systemic blood pressure, BMI and presence of diabetes mellitus were positively associated with mean IOP of elderly Iranian population. Sex and tobacco smoking were not correlated with IOP.<b><i><span style="color:#0033cc"></span></i></b></span></span></span><br> &nbsp; Intraocular Pressure, Intraocular Hypertension, Ocular Tonometry, Glaucoma, Cohort study, Body Mass Index, Diabetes Mellitus, Blood Pressure 112 120 http://caspjim.com/browse.php?a_code=A-10-281-5&slc_lang=en&sid=1 MohammadJavad Ghanbarnia mj.ghanbarnia@gmail.com 100319475328460040857 100319475328460040857 No Student Research Committee, Health Research Center, Babol University of Medical Sciences, Babol, Iran Nour Mohammad Panahi nourm.panahi@gmail.com 100319475328460040858 100319475328460040858 No Student Research Committee, Health Research Center, Babol University of Medical Sciences, Babol, Iran Seyed Ahmad Rasoulinejad rasolisa2@gmail.com 100319475328460040859 100319475328460040859 Yes Department of Ophthalmology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Seyed Reza Hosseini Hosseinirezaseyed@gmail.com 100319475328460040860 100319475328460040860 No Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Hoda Shirafkan hodashirafkan@gmail.com 100319475328460040861 100319475328460040861 No Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Gholam Abbas Roustaei Roustaei1702@yahoo.com 100319475328460040862 100319475328460040862 No Department of Ophthalmology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Ebrahim Mikaniki dr_emikaniki@yahoo.com 100319475328460040863 100319475328460040863 No Department of Ophthalmology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Mehrnoosh Ghasemi mehrnoosh.ghasemi@yahoo.com 100319475328460040864 100319475328460040864 No Department of Ophthalmology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Reza Ghadimi rezaghadimi@yahoo.com 100319475328460040865 100319475328460040865 No Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Ali Bijani Alibijani@yahoo.com 100319475328460040866 100319475328460040866 No Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran