en Infectious Diseases Infectious Diseases Case Series Case Series <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="color:#0000ff;"><strong><em>Background:</em> </strong></span>In COVID-19 pneumonia, chest CT scan plays a crucial role in diagnosing and closely monitoring lung parenchyma. The main reportedly chest CT features of novel coronavirus pneumonia (NCP) have been fully discussed in the literature, but there is still a paucity of reports on uncommon CT manifestations. &nbsp;<br> <span style="color:#0000ff;"><strong><em>Case presentation:</em></strong> </span>Herewith, we have reported ten rRT-PCR confirmed COVID-19 patients with CT target signs (bull&rsquo;s eye appearance); additionally, we have reviewed previously reported cases. Reviewing the literature, we found eight COVID-19 patients with target sign in the literature. 18 patients were included with a median age of 43. 11 (61%) patients were males. In 87% of patients, the lesions developed within the second-week post symptom onset. These patients mostly experienced an extended hospital stay (median = 10 days), with 53.8% of cases being admitted in ICU. The in-hospital mortality rate was 23%.<br> <span style="color:#0000ff;"><strong><em>Conclusion:</em></strong></span> Our findings indicate that lesions with a bull&rsquo;s eye appearance are not significantly associated with higher mortality in hospitalized COVID-19 patients.</span></span> severe acute respiratory syndrome coronavirus 2, COVID-19, CT scan, pneumonia 270 276 http://caspjim.com/browse.php?a_code=A-10-2262-1&slc_lang=en&sid=1 Mohammad-Mehdi Mehrabi Nejad 2m.mehrabi@gmail.com 100319475328460035584 100319475328460035584 No Department of Radiology, School of Medicine, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran Mohammadreza Salehi Salehi.mohamad3@gmail.com 100319475328460035585 100319475328460035585 No Department of Infectious Diseases and Tropical Medicines, Tehran University of Medical Sciences, Tehran, Iran Javid Azadbakht Javidazadbakht2@gmail.com 100319475328460035586 100319475328460035586 No Department of Radiology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran Zahra Jahani Zahra_jahani1992@yahoo.com 100319475328460035587 100319475328460035587 No Department of Infectious Diseases and Tropical Medicines, Tehran University of Medical Sciences, Tehran, Iran Parastoo Veisi parastooveisi2@gmail.com 100319475328460035588 100319475328460035588 No Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran Nahid Sadighi sadighii@yahoo.com 100319475328460035589 100319475328460035589 No Department of Radiology, School of Medicine, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran Faeze Salahshour f-salahshour@sina.tums.ac.ir 100319475328460035590 100319475328460035590 Yes Department of Radiology, School of Medicine, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran