en Neurology Neurology Case Series Case Series <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="color:#0000ff;"><strong><em>Background</em></strong><em>:</em></span> As a global health pandemic, the novel severe acute respiratory syndrome-coronavirus 2 (SARS- CoV2) outbreak began in December 2019 which rapidly spread to more than 200 countries. Respiratory complications and fever are the most obvious symptoms. Sometimes the neurological features are superimposed on the main disease and complicate patient&#39;s status.<br> <span style="color:#0000ff;"><strong><em>Case Presentation</em></strong><em>:</em> </span>We describe 6 patients with COVID-19 and concomitant quadriparesia who underwent electrodiagnosis using EMG/NCS and results indicated 3 axonal variants of Guillain&ndash;Barr&eacute; syndrome (GBS), including; 2 cases AMAN (acute motor axonal neuropathy), 1 case AMSAN (acute motor and sensory axonal neuropathy), three myopathies, including one combination of CIN/CIM (critical illness neuropathy/critical illness myopathy), one CIM and one acute polymyositis in these cases.<br> <span style="color:#0000ff;"><strong><em>Conclusion</em></strong><em>:</em> </span>Early diagnosis of the neuromuscular disorders of coronavirus could help for correct planning in the treatment of COVID-19 patients. Since GBS and inflammatory myopathies have an autoimmune basis, the immunotherapies such as IVIG, steroids, plasma exchange and other novel treatments as hemoperfusion can promise better and faster recovery in respiratory function and neuromuscular activity among COVID-19 patients who have musculature paralysis concomitantly. However, all these treatments are challenging and further clinical trials should be done to confirm the efficacy and safety of mentioned therapies.</span></span> Acute Motor Axonal Neuropathy, COVID-19, Corona virus, Critical illness myopathy, Critical illness neuropathy, GBS, Quadriparesis. 451 459 http://caspjim.com/browse.php?a_code=A-10-2039-1&slc_lang=en&sid=1 Fariba Eslamian fariba_eslamian@yahoo.com 100319475328460031233 100319475328460031233 Yes Physical Medicine and Rehabilitation Research Center, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran Negar Taleschian-Tabrizi 100319475328460031234 100319475328460031234 No Physical Medicine and Rehabilitation Research Center, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran Behzad Izadseresht 100319475328460031235 100319475328460031235 No Physical Medicine and Rehabilitation Research Center, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran Seyyed Kazem Shakouri 100319475328460031236 100319475328460031236 No Physical Medicine and Rehabilitation Research Center, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran Shakiba Gholian 100319475328460031237 100319475328460031237 No Physical Medicine and Rehabilitation Research Center, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran Mohammad Rahbar 100319475328460031238 100319475328460031238 No Physical Medicine and Rehabilitation Research Center, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran