en Infectious Diseases Infectious Diseases Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="color:#0033ff;"><strong><em>Background</em></strong><em>:</em> </span>The New coronavirus (SARS COV-2) can cause acute respiratory disease and also multiorgan dysfunction. There is insufficient data about kidney involvement in children. So, this study was done on children with COVID-19 to evaluate nephrological involvement.<br> <span style="color:#0033ff;"><strong><em>Methods</em></strong><em>:</em></span> All children with confirmed or suspected COVID-19 who were admitted in Children Hospital <span dir="RTL">.</span>were enrolled. They were admitted in hospital from March 2020 to July 2020. Serum Blood Urea Nitrogen (BUN), creatinine, sodium, potassium, calcium and urinalysis were evaluated. Also, glomerular filtration rate (GFR) was calculated by Schertz&#39;s formula. All patients were evaluated by chest x-ray and/or computerized tomography scanning (CTS). The data were analyzed by SPSS software and P value less than 0.05 was determined as significant.<br> <span style="color:#0033ff;"><strong><em>Results</em></strong><em>:</em></span> Forty-seven children with confirmed or suspected COVID-19 were enrolled to this study. At admission, 23.4% and 27.7% of children with COVID-19 had abnormal increase in serum BUN and creatinine, respectively. Also 78.8% and 25.5% of children had GFR less than 90 and 60 ml/min /1.732, respectively. Additionally, 13/47 (27.7%) of children had abnormal urine analysis (microscopic hematuria and/or proteinuria). There wasn&rsquo;t a significant relationship between pulmonary lesions and abnormal reduction of GFR (P<0/05).<br> <span style="color:#0033ff;"><strong><em>Conclusion</em></strong><em>:</em></span> In the study, the risk of AKI (acute kidney injury) and decrease of GFR and also abnormal urinalysis is high in children with COVID-19. So, more attention for detection of kidney involvement is necessary and more conservative management for prevention of AKI and decrease of GFR are recommended.</span></span><br> <span dir="RTL"></span> COVID-19, renal failure, pediatrics, kidney involvement  193 198 http://caspjim.com/browse.php?a_code=A-10-1412-2&slc_lang=en&sid=1 Hadi Sorkhi hadisorkhi@yahoo.com 100319475328460035485 100319475328460035485 No Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Mohamadreza esmaeilidooki esmaeilidooki@yahoo.com 100319475328460035486 100319475328460035486 No Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Maryam Nikpour maryamnikpour19@yahoo.com 100319475328460035487 100319475328460035487 Yes Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Mohsen Mohammadi dr.mohamadi61@yahoo.com 100319475328460035488 100319475328460035488 No Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Ali Mohammadpour-Mir5 alimmir41@gmail.com 100319475328460035489 100319475328460035489 No Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Masood Kiani kianimasood@yahoo.com 100319475328460035490 100319475328460035490 No Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Sanaz Mehrabani mehrabanisanaz@yahoo.com 100319475328460035491 100319475328460035491 No Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Sahar Sadr Moharerpour drsaharsadr@gmail.com 100319475328460035492 100319475328460035492 No Clinical Research Development Center, Amircola Children's Hospital, Babol University of Medical Sciences, Babol, Iran Morteza Alijanpour m.alijanpour@yahoo.com 100319475328460035493 100319475328460035493 No Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Kazem Babazadeh kbabazadeh@hotmail.com 100319475328460035494 100319475328460035494 No Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Hassan Mahmoodi-Nesheli mahmoodi86@yahoo.com 100319475328460035495 100319475328460035495 No Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Mohamadreza Tabatabaie m.tabatabaie_dr@yahoo.com. 100319475328460035496 100319475328460035496 No Clinical Research Development Center, Amircola Children's Hospital, Babol University of Medical Sciences, Babol, Iran Ahmad Tamaddoni drtamaddoni@yahoo.com 100319475328460035497 100319475328460035497 No Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Mohammadreza Salehiomran salehiomran@yahoo.com 100319475328460035498 100319475328460035498 No Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Paiam Payandeh dr.payandeh@gmail.com 100319475328460035499 100319475328460035499 No Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Iraj Mohammadzadeh irjmoh2000@yahoo.com 100319475328460035500 100319475328460035500 No Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Sareh Hosseinpour hosseinpour.sare@gmail.com 100319475328460035501 100319475328460035501 No Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran