en Endocrinology Endocrinology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="color:#0000ff;"><strong><em>Background</em></strong><em>:</em></span> Aging in men causes a gradual decline in endogenous testosterone levels, which may have detrimental effects on their health status. Testosterone deficiency is thought to promote atherosclerosis by modulating lipid metabolism. Therefore, this study was conducted to evaluate the serum testosterone level and its correlation with lipid profile in men aged &ge;60 years old.<br> <span style="color:#0000ff;"><strong><em>Methods</em></strong><em>:</em></span> All elderly men aged &ge;60, residing in Amirkola and participating in a phase of the comprehensive project on &quot;investigating the health status of the elderly in Amirkola&quot; were entered into this descriptive cross-sectional study. After fasting over 12 hours, the venous blood samples were taken. Serum concentration of testosterone was determined using ELISA method. Moreover, HDL-LDL, total cholesterol, triglyceride and fasting blood glucose were measured.<br> <span style="color:#0000ff;"><strong><em>Results</em></strong><em>:</em></span> The prevalence of hypogonadism was 91.28% among the 792 participants of this study with a cut-off point of 9.72 nmol/L (95% confidence interval, 93.25-89.31) and the prevalence of severe hypogonadism with a cut-off point of 5.2 nmol/L was reported 71.59% (95% confidence interval, 74.73-68.44%). Based on the results, there was no significant statistical correlation between the serum level of testosterone and triglyceride (r=0.03, P=0.34). Furthermore, there was a negative correlation between testosterone and HDL, which was not statistically significant(r=-0.05, P=0.13). No significant statistical correlation was found between testosterone and LDL (P=0.98). There was a negative correlation between testosterone and cholesterol, which was not statistically significant (r=-0.02, P=0.49).<br> <span style="color:#0000ff;"><strong><em>Conclusion</em></strong><em>:</em></span> According to the study results, 91% of men aged &ge;60 years old had hypogonadism, no correlation was found between testosterone and lipid indices.</span></span> Testosterone, Men, Lipid indices, Hypogonadism 135 139 http://caspjim.com/browse.php?a_code=A-10-1533-1&slc_lang=en&sid=1 Neda Meftah nedameftah@yahoo.com 100319475328460028131 100319475328460028131 No Clinical Research Development Center, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran Ali Bijani alibijani@yahoo.com 100319475328460028132 100319475328460028132 No Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Seyed reza Hosseini seidrezahosseini@yahoo.com 100319475328460028133 100319475328460028133 No Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Amirmorteza Soleymani rohanresearch88@gmail.com 100319475328460028134 100319475328460028134 Yes Student Committee Research, Babol University of Medical Sciences, Babol, Iran