en Cardiology Cardiology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> <span lang="EN">Abnormality in the cardiovascular system such as left ventricular dysfunction caused increased serum CRP and change in electrocardiography pattern. The present study aimed to understand the association between increased levels of highly sensitive CRP (hs-CRP) and non-arrhythmic ECG changes and electrocardiographic abnormalities in patients with the acute coronary syndrome.</span><span style="font-size:9.0pt"></span></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Methods:</span></i></b> <span lang="EN">This study was done on 120 patients diagnosed with acute coronary syndrome and hospitalized at CCU. The patients were classified into two groups, one group with an increased level of hs-CRP and another with a normal hs-CRP level.</span><span lang="EN" style="font-size:10.0pt"></span></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Results:</span></i></b> <span lang="EN">The patients with an increased level of hs-CRP showed a significantly higher level of cardiac enzymes also ST-segment elevation myocardial infarction (STEMI) was seen in the group with an increased level of hs-CRP than those with normal serum hs-CRP level, but another diagnosis including unstable angina, non-STEMI, heart failure, and emergency hypertension was similarly observed in both groups. Two groups were assessed in terms of left ventricular ejection fraction (LVEF), left ventricular end-diastolic diameter (LVeDD) the prevalence of valvular heart disease, and wall motion abnormality, also showed that groups with increased hs-CRP level, ST-segment elevation leads more significant differences than a normal group (P=0.001).</span><b><i><span style="color:blue"></span></i></b></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Conclusion</span></i></b><i><span style="color:blue">:</span></i> <span lang="EN">Patients </span><span lang="EN">with an increased level of hs-CRP can be diagnosed as STEMI but not</span><span lang="EN"> valuable to </span><span lang="EN">suppose as echocardiographic abnormalities such as left ventricular dysfunction or hypertrophy.</span><b><i><span style="color:#0033cc"></span></i></b></span></span></span><br> &nbsp; CRP, acute coronary syndrome, ECG, myocardial infarction 83 88 http://caspjim.com/browse.php?a_code=A-10-1359-2&slc_lang=en&sid=1 Roholla Hemmati roholahemmati@gmail.com 100319475328460040836 100319475328460040836 No Department of Cardiology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran Yousof mohsenzadeh ymohsenzadeh1979@gmail.com 100319475328460040837 100319475328460040837 Yes Department of Cardiology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran Reza madday r_madady2000@yahoo.com 100319475328460040838 100319475328460040838 No Department of Cardiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran