en Health Health Original Article Original Article <span style="font-size:12px;"><span style="font-family:times new roman;"><span style="color:#0000FF;"><strong><em>Background</em></strong><em>:</em> </span>The epidemic of obesity has turned into a major global health challenge. Environmental and social factors such as social capital, can significantly affect obesity. This study aimed to evaluate the relationship of social capital with overweight and obesity among female health-care workers.<br> <span style="color:#0000FF;"><strong><em>Methods</em></strong><em>:</em></span> This cross-sectional study was conducted in 2018 on 680 female health-care workers who were randomly selected from healthcare settings affiliated to Babol University of Medical Sciences, Babol, Iran. Data were collected using a demographic questionnaire and the Workplace Social Capital (WSC) questionnaire. The SPSS Version 21 was employed to analyze the data through conducting the independent-sample <em>t</em> and the chi-square tests as well as the linear and the logistic regression analyses at a significance level of less than 0.05.<br> <span style="color:#0000FF;"><strong><em>Results</em></strong><em>:</em></span> Linear regression analysis revealed that age, marital status, satisfaction with economic status, and structural social capital were significant predictors of body mass index (P<0.05). Moreover, logistic regression analysis indicated that weak social capital increased the odds of overweight/ obesity by 1.3 times (OR=1.345; 95% CI: 0.643&ndash;2.812) and weak structural social capital significantly increased the odds of overweight /obesity by almost four times (OR=3.757; 95% CI: 1.628&ndash;8.671; P=0.002).<br> <span style="color:#0000FF;"><strong><em>Conclusion</em></strong><em>:</em></span> Social capital, particularly structural social capital, is a significant predictor of body mass index and a protective factor against obesity among female health-care workers. Further studies are needed to determine the paths through which social capital affects obesity- and overweight-related behaviors.ش</span></span> Overweight, Obesity, Social capital, Female workers, Iran. 281 288 http://caspjim.com/browse.php?a_code=A-10-1299-1&slc_lang=en&sid=1 Mojgan Firouzbakht Firouzbakht_m@yahoo.com 100319475328460018057 100319475328460018057 No Social Determinant of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Mohammad Esmaeil Riahi m.riahi@umz.ac.ir 100319475328460018058 100319475328460018058 No Department of Social Sciences, University of Mazandaran, Babolsar, Iran Karimollah Hajian-Tilaki drhajian@yahoo.com 100319475328460018059 100319475328460018059 No Social Determinant of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Abbas Ebadi ebadi1347@bmsu.ac.ir 100319475328460018060 100319475328460018060 No Behavioral Sciences Research Center, Life style Institiute, Nursing Faculty, Baqiyatallah University of Medical Sciences, Nursing Faculty, Tehran, Iran Aram Tirgar a.tirgar@mubabol.ac.ir 100319475328460018061 100319475328460018061 Yes Social Determinant of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Maryam Nikpour 100319475328460018062 100319475328460018062 No Social Determinant of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran