en Internal Internal Original Article Original Article <span style="font-size: 14px;"><span style="font-family: times new roman;"><span style="color: rgb(0, 0, 255);"><strong><em>Background</em></strong><em>:</em></span> Metal phosphides are widely used as a rodenticide and insecticide and poisoning with these substances has a very high mortality. The aim of this study was to evaluate the butyrylcholinesterase (BuCh) level in poisoning with metal phosphides.<br> <span style="color: rgb(0, 0, 255);"><strong><em>Methods</em></strong><em>:</em> </span>In this case series study, 60 poisoned patients with zinc phosphide (ZnP) and aluminum phosphide (ALP) who was admitted to poisoning ward in Hamadan,&nbsp;Iran, enrolled in the study and BuCh level was measured. The sex, age, amount of ingestion, time of consumption, signs and symptoms, ECG and arterial blood gas (ABG) changes and clinical outcomes were evaluated.<br> <span style="color: rgb(0, 0, 255);"><strong><em>Results</em></strong><em>:</em></span> Most (58.3%) patients were males, the mean age was 32.76&plusmn;17.65 years. The average amount of ingestion was 7.5&plusmn;4.6 and 2.5&plusmn;2.96 gr for ZnP and ALP, respectively. Most signs and symptoms were hypotension (97%), nausea and vomiting (82%) and abdominal pain (32%). The average amount of BuCh level in all patients was 5163.25&plusmn;2158.31 U/L, that&#39;s while in ZnP and ALP poisoned patients was 5608&plusmn;1577 U/L and 4721.46&plusmn;2562U/L respectively. The most dysrhythmia (26.7%) was sinus tachycardia. Acidosis was seen in 33.3% of patients. 14 patients died after hospital admission, which caused a 23.3% fatality rate.<br> <span style="color: rgb(0, 0, 255);"><strong><em>Conclusion</em></strong><em>:</em> </span>Our results showed that, there was no significant change in BuCh level in poisoned patients with phosphide compounds.</span></span> Zinc Phosphide, Aluminum Phosphide, Butyrylcholinesterase. 458 462 http://caspjim.com/browse.php?a_code=A-10-1285-1&slc_lang=en&sid=1 Saeed Afzali afzali691@yahoo.com 100319475328460018867 100319475328460018867 Yes Department of Forensic Medicine and Toxicology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran Seyed Kazem Taheri saeid_tm@yahoo.com 100319475328460018868 100319475328460018868 No Department of Forensic Medicine and Toxicology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran Mohamadali Seifrabiei seifrabiei@yahoo.com 100319475328460018869 100319475328460018869 No Department of Community Medicine, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran