en Pathology Pathology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:150%"><span style="color:#0033ff;"><b><i><span style="line-height:150%">Background</span></i></b></span><i><span style="line-height:150%"><span style="color:#0033ff;">:</span> </span></i><span style="line-height:150%">Vaccination has reduced the viral respiratory diseases in the community, but it has not ended. This study was conducted to determine the distribution of COVID-19, the influenza virus, and the human respiratory syncytial virus (RSV). </span></span><br> <span style="line-height:150%"><span style="color:#0033ff;"><b><i><span style="line-height:150%">Methods:</span></i></b></span><span style="line-height:150%"> This retrospective, descriptive-analytical study was conducted based on patient file information in Babol City (2021-2024). Clinical examination of the patient, computed tomography (CT), and real-time polymerase chain reaction (PCR) were used to identify the viruses in 10,567 patients. Mean, standard deviation (SD), distribution (%), and logistic regression were used to analyze the data using SPSS-23 (p<0.05). </span></span><br> <span style="line-height:150%"><span style="color:#0033ff;"><b><i><span style="line-height:150%">Results:</span></i></b></span><span style="line-height:150%"> 83.34% and 16.65% of patients suffered from COVID-19 (12.95% &ge; 50 years old) and influenza (15.42%, &le; 50 years old), respectively. The most underlying diseases were related to cardiovascular disease (17.47%). Female patients suspected of<b> </b>COVID-19 (females; 14.14% versus (vs) males; 11.87%) and influenza (females; 14.90% vs males; 15.62%) were more than male patients. COVID-19 (12.91%) and influenza (15.27%) in 2022 and 2023 showed a high distribution, respectively. Co-occurrence of COVID-19 and influenza was observed in one female. Gender, season, and year (each with a p-value of P=0.00) was associated in this descriptive analysis with the distribution of COVID-19. A significant relationship between season and year (each one P-value=0.00=0.00) with the distribution of influenza was observed.<span style="font-family:&quot;Times New Roman&quot;,serif"></span></span></span><br> <span style="line-height:150%"><span style="color:#0033ff;"><b><i><span style="line-height:150%">Conclusion</span></i></b></span><i><span style="line-height:150%"><span style="color:#0033ff;">:</span> </span></i><span style="line-height:150%">A high distribution of COVID-19 was diagnosed among patients. Gender and year of study had a significant effect on COVID-19. Diagnosis and differentiation of the viral agent by molecular methods should be performed in a patient.</span></span></span></span><br> &nbsp; Viral Respiratory Infections, Influenza, Coronavirus-2019, Human Respiratory Syncytial Virus. 20 0 http://caspjim.com/browse.php?a_code=A-10-2423-4&slc_lang=en&sid=1 Alireza Firouzjahi firouzal@hotmail.com 100319475328460056497 100319475328460056497 No Clinical Research Development Unit, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Samaneh Rouhi roohi.samaneh@yahoo.com 100319475328460056498 100319475328460056498 No Clinical Research Development Unit, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Mohammad Ranaee microbiol_sci@yahoo.com 100319475328460056499 100319475328460056499 No Clinical Research Development Unit, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Zahra Ahmadnia sama_tanha0123@yahoo.com 100319475328460056500 100319475328460056500 No Clinical Research Development Unit, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Mahdieh Taheri nazanin.taheri75@gmail.com 100319475328460056501 100319475328460056501 No Clinical Research Development Unit, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Sara Ghofrani Tabari sara.ghofrani76@gmail.com 100319475328460056502 0009-0003-6317-4569 No Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran. Somayeh Ahmadi Gooraji ahmadisomayeh90@gmail.com 100319475328460056503 100319475328460056503 No Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran Hossein Ghorbani ghorbani7958@yahoo.com 100319475328460056504 100319475328460056504 Yes Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.